I’ve seen some players debate which is better. Condition Overload is better in the majority of cases. It basically matches primed pressure point if the enemy has 2 different statuses on them. Many melee stance mods have attacks that guarantee a status effect, your companion can apply status effects, the people you’re playing with can apply status effects, and so on.
The only situation where primed pressure point is better is if the first attack can kill the enemy with primed pressure point and condition overload can’t and you are playing solo while not applying any statuses yourself.
This is not a post about what the best build is for any specific weapon or a hard and fast rule. Just a general rule of thumb if you are choosing which one of the two to put into a slot.
Edit: a general rule of thumb for a standard melee weapons. As pointed out below condition overload may not work with all exalted abilities.
The pressure point mods are usually more useful against status immune enemies, some enemies are only immune to certain status effects, so CO could be better depending on what elements you have. CO also doesn’t work with every pseudo exalted ability, so if you’re lazy like me and don’t want to check if it’s compatible, it’s easier to just grab a weapon with pressure point.